Description

4-(Acetylamino)-5-Chloro-n-[2-(Diethylamino)Ethyl]-2-Methoxybenzamide is a specialized organic compound with a complex molecular structure featuring acetylamino, chloro, and diethylaminoethyl functional groups. This compound is valued for its role as a key synthetic intermediate in the development of pharmacologically active molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the synthesis and process development of new chemical entities, particularly those targeting neurological or gastrointestinal receptors.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potential drug candidates, especially in medicinal chemistry research.
• Biochemical Research: Used as a reference standard or reagent in studies investigating structure-activity relationships (SAR) for specific biological targets.
• Process Development: Employed in scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs) within pilot plants.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific benzamide derivative.

Basic Information

Product Name	4-(Acetylamino)-5-Chloro-n-[2-(Diethylamino)Ethyl]-2-Methoxybenzamide
CAS No.	5608-13-9
Molecular Formula	C16H24ClN3O3
Molecular Weight	341.84 g/mol
Synonyms	5-Chloro-2-methoxy-N-[2-(diethylamino)ethyl]-4-acetamidobenzamide; N-[2-(Diethylamino)ethyl]-5-chloro-2-methoxy-4-acetamidobenzamide; 4-Acetamido-5-chloro-2-methoxy-N-[2-(diethylamino)ethyl]benzamide; Benzamide, 4-(acetylamino)-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-; A-4166; AD-1211; Itopride Intermediate; CAS 5608-13-9
EINECS	Contact for details

Quality Control

Our production of 4-(Acetylamino)-5-Chloro-n-[2-(Diethylamino)Ethyl]-2-Methoxybenzamide adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established internal specifications, which are aligned with cGMP principles for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.