Description

2,5-Dichlorobenzenesulfonyl Chloride is a versatile and highly reactive organosulfur compound primarily used as a key sulfonylation reagent and synthetic intermediate. Its value lies in its ability to introduce the sulfonyl chloride functional group into target molecules, enabling the synthesis of sulfonamides and other sulfonyl derivatives critical for advanced material and pharmaceutical development. This chemical is essential for researchers and manufacturers in the agrochemical, pharmaceutical, and specialty chemical industries who require a reliable, high-purity building block for complex synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating sulfonamide-based drugs with antibacterial, diuretic, or anti-inflammatory properties.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where the sulfonyl moiety contributes to biological activity and selectivity.
• Dyestuff and Pigment Manufacturing: Acts as an intermediate in the synthesis of sulfonated dyes and organic pigments, enhancing color fastness and solubility.
• Polymer Modification: Employed to introduce sulfonyl chloride groups into polymer chains, leading to functional materials with altered properties like ion-exchange capacity or improved adhesion.
• Chemical Research & Development: A valuable reagent in organic synthesis laboratories for constructing complex molecular architectures and exploring new reaction pathways.
• Liquid Crystal and Electronic Material Precursor: Used in the synthesis of specialized organic compounds for electronic applications, including liquid crystal displays (LCDs).

Basic Information

Product Name	2,5-Dichlorobenzenesulfonyl Chloride
CAS No.	5402-73-3
Molecular Formula	C6H3Cl3O2S
Molecular Weight	245.51 g/mol
Synonyms	2,5-Dichlorobenzene-1-sulfonyl chloride; 1,4-Dichloro-2-sulfonylchlorobenzene; Benzenesulfonyl chloride, 2,5-dichloro-; 2,5-Dichlorophenylsulfonyl chloride; 2,5-DCBSCl; 2,5-Dichlorobenzenesulphonyl chloride; NSC 403108
EINECS	226-456-8

Quality Control

Our 2,5-Dichlorobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and reactive nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to minimize moisture absorption and decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.