Description

Isobutyl β-D-Glucuronide is a high-purity biochemical reagent and a crucial derivative of glucuronic acid. This compound serves as a vital intermediate and reference standard in advanced pharmaceutical research and analytical chemistry. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications such as drug metabolism studies and enzyme substrate development.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification and qualification of drug metabolites in bioanalytical methods like LC-MS and HPLC.
• Biochemical Research: Acts as a substrate or intermediate in enzymatic studies, particularly for glucuronosyltransferase (UGT) assays and metabolic pathway investigations.
• Drug Metabolism & Pharmacokinetics (DMPK): Essential for studying Phase II drug conjugation (glucuronidation) to understand drug clearance, bioavailability, and metabolite profiling.
• Diagnostic Reagent Manufacturing: Employed in the synthesis of key components for clinical diagnostic kits that measure specific enzymes or metabolic markers.
• Academic Research: Utilized in universities and research institutes for projects related to carbohydrate chemistry, glycosylation processes, and biomarker discovery.

Basic Information

Product Name	Isobutyl β-D-Glucuronide
CAS No.	5391-15-1
Molecular Formula	C₁₀H₁₈O₇
Molecular Weight	250.24 g/mol
Synonyms	Isobutyl β-D-Glucopyranosiduronic Acid; β-D-Glucopyranosiduronic Acid, Isobutyl Ester; Isobutyl Glucuronide; 1-O-Isobutyl-β-D-glucuronic Acid; Glucuronic Acid Isobutyl Ester; D-Glucuronic Acid, Isobutyl Glycoside
EINECS	Contact for details

Quality Control

Our Isobutyl β-D-Glucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.