Description

1,2,3,5-Tetrafluoro-4-Trifluoromethyl-Benzene is a highly fluorinated aromatic compound, serving as a critical building block in advanced chemical synthesis. Its unique perfluorinated aromatic structure makes it an invaluable intermediate for creating complex molecules with enhanced stability and specific electronic properties. This compound is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the trifluoromethyl and tetrafluoroaryl groups into drug candidates, enhancing metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides where fluorine substitution is crucial for bioactivity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a core component in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving electronic properties and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart chemical resistance, thermal stability, and low surface energy characteristics.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex fluorinated architectures.
• Refrigerant & Propellant Research: Investigated as a potential component in next-generation, environmentally friendly refrigerant blends due to its fluorocarbon content.

Basic Information

Product Name	1,2,3,5-Tetrafluoro-4-Trifluoromethyl-Benzene
CAS No.	5360-82-7
Molecular Formula	C7HF7
Molecular Weight	218.07 g/mol
Synonyms	Pentafluorobenzotrifluoride; 1,2,3,5-Tetrafluoro-4-(trifluoromethyl)benzene; 4-(Trifluoromethyl)-1,2,3,5-tetrafluorobenzene; Benzene, 1,2,3,5-tetrafluoro-4-(trifluoromethyl)-; α,α,α,2,3,5,6-Heptafluorotoluene; Heptafluorotoluene (common name); Perfluorotoluene (historical/incorrect but used); NSC 9235
EINECS	226-341-5

Quality Control

Our 1,2,3,5-Tetrafluoro-4-Trifluoromethyl-Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability, though short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.65 g/mL
Boiling Point	~115-117°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.