Description

3-(Methylsulfonyl)Benzenesulfonylchloride is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its value lies in its dual functional groups, which enable precise and efficient sulfonylation reactions for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, particularly sulfonamide-based drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel sulfonamide drugs, including diuretics, carbonic anhydrase inhibitors, and antibacterial agents.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and pesticides that require specific sulfonyl moiety incorporation.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing sulfonated dyes and specialty pigments with enhanced properties.
• Polymer Chemistry: Employed in the creation of specialty polymers and functional materials, such as ion-exchange resins and polymeric sulfonamides.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.
• Ligand and Catalyst Design: Useful for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.

Basic Information

Product Name	3-(Methylsulfonyl)Benzenesulfonylchloride
CAS No.	5335-40-0
Molecular Formula	C7H7ClO4S2
Molecular Weight	254.71 g/mol
Synonyms	3-(Methanesulfonyl)benzenesulfonyl chloride; m-(Methylsulfonyl)benzenesulfonyl chloride; Benzenesulfonyl chloride, 3-(methylsulfonyl)-; 3-Methylsulfonylbenzenesulfonyl chloride; 3-(Methylsulfonyl)phenylsulfonyl chloride; 1-Chlorosulfonyl-3-methanesulfonylbenzene; Meta-(methylsulfonyl)benzenesulfonyl chloride
EINECS	226-245-5

Quality Control

Our 3-(Methylsulfonyl)Benzenesulfonylchloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.