Description

Phylloquinone-Ar,Ar,Ar,Ar-D4 (7Ci,8Ci) is a high-purity, deuterium-labeled isotopologue of Vitamin K1, a critical compound in biochemical research and analytical chemistry. This stable isotope-labeled standard is essential for ensuring accuracy and reliability in quantitative mass spectrometry analyses. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, nutraceutical, and life science sectors who require precise internal standards for method development and validation.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative reference for the accurate measurement of endogenous Vitamin K1 levels in biological matrices such as plasma, serum, and tissues.
• Metabolic Pathway Tracing: Used in pharmacokinetic and metabolic studies to track the absorption, distribution, metabolism, and excretion (ADME) of Vitamin K1 and related compounds.
• Method Development & Validation: Essential for developing and validating robust, high-sensitivity analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Clinical Research: Supports studies investigating Vitamin K status, bone health, cardiovascular function, and coagulation disorders.
• Food & Nutritional Analysis: Enables precise quantification of Vitamin K1 in fortified foods, dietary supplements, and infant formula.
• Pharmaceutical Quality Control: Used in the assay and impurity profiling of pharmaceutical products containing Vitamin K.

Basic Information

Product Name	Phylloquinone-Ar,Ar,Ar,Ar-D4 (7Ci,8Ci)
CAS No.	5172-18-9
Molecular Formula	C₃₁H₄₂D₄O₂
Molecular Weight	454.70 g/mol
Synonyms	Vitamin K1-d4; Phylloquinone-d4; 2-Methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]naphthoquinone-d4; 3-Phytylmenadione-d4; 2-Methyl-3-phytyl-1,4-naphthoquinone-d4; Menaquinone-0-d4; Konakion-d4; Phytomenadione-d4
EINECS	Contact for details

Quality Control

Every batch of Phylloquinone-Ar,Ar,Ar,Ar-D4 (7Ci,8Ci) is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for isotopic purity and chemical identity in research applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters including isotopic enrichment (D-Atom %), chemical purity, and confirmation of structure.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep the container sealed in a dry, cold environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange viscous oil or solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-Atom %)	≥ 98.0%
Chemical Purity (by GC)	≥ 98.0%
Solubility	Soluble in ethanol, DMSO, chloroform

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.