Description

Succinic Acid, [2,3-14C] is a high-purity, carbon-14 labeled isotopologue of succinic acid, a key intermediate in the citric acid cycle. This radiolabeled compound is essential for advanced metabolic and pharmacokinetic studies, providing researchers with a precise tracer to elucidate biochemical pathways. It is a critical tool for scientists in pharmaceutical R&D, agrochemical development, and biochemistry who require definitive data on compound metabolism, degradation, and environmental fate.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer in in vitro and in vivo studies to map the metabolic fate of succinic acid and related compounds within the Krebs cycle.
• Drug Metabolism and Pharmacokinetics (DMPK): Enables precise quantification of absorption, distribution, metabolism, and excretion (ADME) for new chemical entities in pharmaceutical development.
• Environmental Fate Studies: Applied in agrochemical research to track the degradation pathways and persistence of chemicals in soil and water systems.
• Biochemical Research: Serves as a substrate in enzymatic assays and studies of mitochondrial function and cellular respiration.
• Synthesis of Labeled Compounds: Acts as a labeled building block for the synthesis of more complex carbon-14 labeled molecules for research purposes.

Basic Information

Product Name	Succinic Acid, [2,3-14C]
CAS No.	5163-60-0
Molecular Formula	C4H614C2O4
Molecular Weight	~120.1 g/mol (exact mass depends on specific activity)
Synonyms	Butanedioic-2,3-14C Acid; Amber Acid-2,3-14C; 1,2-Ethanedicarboxylic-2,3-14C Acid; [2,3-14C]Succinic Acid; Radiolabeled Succinic Acid; Carbon-14 Labeled Succinate; Succinic-2,3-14C Acid
EINECS	Contact for details

Quality Control

Every batch of Succinic Acid, [2,3-14C] is manufactured and analyzed under strict quality control protocols to ensure high chemical and radiochemical purity, specific activity, and stability. Our products undergo rigorous testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, specific activity (mCi/mmol or GBq/mmol), radiochemical concentration, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) to maintain stability and specific activity. Keep away from incompatible materials. Handle and store in accordance with all local, national, and international regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR/NMR)	Conforms to structure
Assay (HPLC)	≥ 98% (Chemical Purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Customizable (e.g., 50-60 mCi/mmol)
Solvent (if supplied in solution)	Specified on COA (e.g., Water, Ethanol)
Concentration (if supplied in solution)	Specified on COA (e.g., 1.0 mCi/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.