Description

3-Methyladenine is a purine derivative and a well-characterized autophagy inhibitor. This compound is a critical research tool for studying cellular degradation pathways and has significant value in biochemical and pharmacological research. It is primarily utilized by researchers in life sciences, pharmaceutical development, and academic institutions investigating autophagy-related diseases and mechanisms.

Application

• Biochemical Research: A standard inhibitor used to study autophagy flux and lysosomal degradation pathways in cell culture models.
• Pharmaceutical Screening: Employed in drug discovery programs targeting autophagy for conditions like cancer, neurodegenerative disorders, and infectious diseases.
• Mechanistic Studies: Used to elucidate the role of autophagy in cellular stress response, aging, and programmed cell death.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic Research: A key reagent in university and institutional labs for graduate and post-doctoral research projects in cell biology.

Basic Information

Product Name	3-Methyladenine
CAS No.	5142-23-4
Molecular Formula	C6H7N5
Molecular Weight	149.15 g/mol
Synonyms	3-MA; 3-Methyl-7H-purin-6-amine; 6-Amino-3-methylpurine; NSC 66389; 3-Methyladenine (autophagy inhibitor); 3-Methyl-9H-purin-6-amine; 3-Methyl-6-aminopurine
EINECS	225-904-5

Quality Control

Our 3-Methyladenine is produced and tested under strict quality management systems. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.