Description

1-Bromo-2-Fluoro-4,5-Dimethylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine substituents on a dimethylbenzene scaffold, enabling selective functionalization for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated organic semiconductors and liquid crystal compounds for display technologies.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Stille couplings to create complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs as a versatile reagent for exploring new synthetic methodologies and creating specialized chemical libraries.
• Fluorinated Polymer Monomers: Acts as a monomer or comonomer precursor in the development of specialty polymers with enhanced chemical resistance and thermal stability.

Basic Information

Product Name	1-Bromo-2-Fluoro-4,5-Dimethylbenzene
CAS No.	5100-97-0
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	2-Bromo-1-Fluoro-4,5-Dimethylbenzene; 4,5-Dimethyl-2-Fluorobromobenzene; 1-Fluoro-2-Bromo-4,5-Dimethylbenzene; 2-Fluoro-4,5-Dimethylbromobenzene; 4,5-Dimethyl-1-Bromo-2-Fluorobenzene; 2-Fluoro-1-Bromo-4,5-Dimethylbenzene; 4,5-Dimethyl-2-Fluorophenyl Bromide
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Fluoro-4,5-Dimethylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.