Description

4-(2-Bromoacetyl)Benzenesulfonyl Chloride is a versatile and highly reactive bifunctional organic intermediate. This compound is valued for its dual reactive sites, the bromoacetyl and sulfonyl chloride groups, which enable its use in sophisticated multi-step synthetic pathways. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides that leverage the sulfonyl moiety for biological activity.
• Chemical Biology & Proteomics: Serves as a reactive handle for affinity-based protein labeling, cross-linking, and the development of activity-based probes (ABPs).
• Material Science: Precursor for modifying polymer surfaces or creating specialized monomers with sulfonyl chloride functionality.
• Custom Synthesis & Contract Research: Employed in research-scale and pilot-scale projects for creating bespoke chemical entities and libraries.
• Peptide Modification: Facilitates the site-specific introduction of reactive ketone or sulfonamide groups into peptides and biomolecules.

Basic Information

Product Name	4-(2-Bromoacetyl)Benzenesulfonyl Chloride
CAS No.	5038-59-5
Molecular Formula	C8H6BrClO3S
Molecular Weight	297.55 g/mol
Synonyms	p-(Bromoacetyl)benzenesulfonyl chloride; 1-(4-(Chlorosulfonyl)phenyl)-2-bromoethan-1-one; 4-Bromoacetylbenzenesulfonyl chloride; 2-Bromo-1-[4-(chlorosulfonyl)phenyl]ethanone; α-Bromo-4-(chlorosulfonyl)acetophenone; 4-(2-Bromoacetyl)phenylsulfonyl chloride; Bromoacetylbenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Bromoacetyl)Benzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.