Description

3-(2-Fluoroethoxy)Propylamine is a versatile fluorinated amine building block characterized by its unique ether-amine structure. This compound is valued for its ability to introduce both fluorine and a primary amine functionality into target molecules, enhancing properties such as metabolic stability, lipophilicity, and bioavailability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for CNS drugs, anticancer agents, and PET (Positron Emission Tomography) tracer molecules.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the fluorine atom can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a functional precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and stability.
• Polymer Modification: Employed to introduce amine and fluoroalkyl ether groups into polymer backbones, altering surface properties, adhesion, and chemical resistance.
• Bioconjugation & Linker Chemistry: The primary amine group is reactive for conjugation with biomolecules (proteins, peptides) or solid supports, while the fluoroethoxy moiety can act as a spacer or modifier.
• Organic Synthesis Building Block: Utilized in various organic transformations, including nucleophilic substitution and reductive amination, to create complex fluorinated molecules for research.

Basic Information

Product Name	3-(2-Fluoroethoxy)Propylamine
CAS No.	593-00-0
Molecular Formula	C5H12FNO
Molecular Weight	121.15 g/mol
Synonyms	1-Amino-3-(2-fluoroethoxy)propane; 3-(2-Fluoroethoxy)-1-propanamine; 2-Fluoroethyl 3-aminopropyl ether; 3-(β-Fluoroethoxy)propylamine; 1-Propanamine, 3-(2-fluoroethoxy)-; FEP; 3-(2-FEA)Propylamine
EINECS	209-788-8

Quality Control

Our 3-(2-Fluoroethoxy)Propylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption. Keep away from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.02 g/cm³
Refractive Index (n20/D)	~1.420

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.