Description

1-(2-Fluoro-5-Methylphenyl)Propan-1-One is a high-purity fluorinated aromatic ketone, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a methyl substituent on the phenyl ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, particularly for molecules requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing to the development of materials with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in various name reactions, such as Friedel-Crafts acylation follow-up chemistry, to introduce the propiophenone moiety into more complex structures.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for method development and exploring new reaction pathways involving fluorinated ketones.

Basic Information

Product Name	1-(2-Fluoro-5-Methylphenyl)Propan-1-One
CAS No.	575-65-5
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	2'-Fluoro-5'-Methylpropiophenone; 1-Propanone, 1-(2-fluoro-5-methylphenyl)-; 2-Fluoro-5-Methylpropiophenone; 1-(2-Fluoro-5-methylphenyl)-1-propanone; Propiophenone, 2'-fluoro-5'-methyl-; 575-65-5; 2-Fluoro-5-methylpropiophenone; 2-Fluoro-5-methyl-1-phenyl-1-propanone
EINECS	Contact for details

Quality Control

Our production of 1-(2-Fluoro-5-Methylphenyl)Propan-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with global regulatory frameworks, and specifications can be aligned with customer-specific requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.