Description

Carbonyl Cyanide 3-Chlorophenylhydrazone is a potent and specific mitochondrial uncoupling agent widely used in biochemical and pharmacological research. Its primary value lies in its ability to dissipate the proton gradient across the inner mitochondrial membrane, effectively inhibiting ATP synthesis. This makes it an indispensable tool for researchers studying cellular bioenergetics, oxidative stress, and metabolic pathways. Key industries that rely on this high-purity reagent include pharmaceutical R&D, academic biochemistry, and biotechnology.

Application

• Mitochondrial Research: A critical tool for studying oxidative phosphorylation, proton leak, and mitochondrial membrane potential in cell biology and biochemistry.
• Metabolic Pathway Analysis: Used to investigate cellular energy metabolism, ATP production, and the role of mitochondria in various disease models.
• Pharmacology & Toxicology: Employed in screening compounds for mitochondrial toxicity and understanding drug-induced metabolic dysfunction.
• Cell Stress & Apoptosis Studies: Applied to induce controlled metabolic stress and study mechanisms of programmed cell death.
• Biochemical Assay Development: Serves as a standard and positive control in assays designed to measure mitochondrial function and respiration.
• Academic & Industrial R&D: Essential for basic research in universities and applied research in pharmaceutical and biotech companies.

Basic Information

Product Name	Carbonyl Cyanide 3-Chlorophenylhydrazone
CAS No.	555-60-2
Molecular Formula	C9H5ClN4O
Molecular Weight	220.62 g/mol
Synonyms	CCCP; Carbonyl cyanide m-chlorophenyl hydrazone; 3-Chlorophenylhydrazonopropanedinitrile; m-Chlorocarbonylcyanide phenylhydrazone; Uncoupler CCCP; Mitochondrial Uncoupler CCCP; 3-Chloro-phenylhydrazono-malononitrile; Carbonylcyanide-3-chlorophenylhydrazone
EINECS	209-095-0

Quality Control

Our Carbonyl Cyanide 3-Chlorophenylhydrazone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability. Keep the container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	190°C - 195°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.