Description

5-α-Pregnan-3-Beta, 17,21-Triol-11,20-Dione is a high-purity steroid derivative and a key intermediate in organic synthesis. This compound is valued for its defined stereochemistry and functional groups, which make it a versatile building block for pharmaceutical research and development. It is primarily utilized by research institutions and manufacturers in the life sciences sector for the synthesis of more complex steroid-based molecules, including potential active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: A critical starting material or intermediate in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and steroid hormone research.
• Organic Synthesis: Serves as a chiral building block for constructing novel molecular architectures in medicinal chemistry programs.
• Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control testing of related steroid compounds.

Basic Information

Product Name	5-α-Pregnan-3-Beta, 17,21-Triol-11,20-Dione
CAS No.	547-77-3
Molecular Formula	C21H32O5
Molecular Weight	364.48 g/mol
Synonyms	11-Deoxycortisol; 17,21-Dihydroxypregn-4-ene-3,11,20-trione; Reichstein's Substance S; 17α,21-Dihydroxy-4-pregnene-3,11,20-trione; 11-Deoxy-17-hydroxycorticosterone; 5α-Pregnane-3β,17α,21-triol-11,20-dione; 21-Hydroxy-4-pregnene-3,11,20-trione
EINECS	208-936-7

Quality Control

Our 5-α-Pregnan-3-Beta, 17,21-Triol-11,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.