Description

Arcaine CAS NO 544-05-8 is a high-purity, synthetic guanidino compound of significant interest in biochemical and pharmacological research. This compound serves as a potent and selective competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor complex, specifically at the polyamine site. It is an essential research tool for neuroscientists and pharmaceutical developers studying excitatory neurotransmission, neuroprotection, and conditions such as stroke, epilepsy, and neurodegenerative diseases. Our supply ensures consistent quality and reliability for critical laboratory and development work.

Application

• Neuroscience Research: As a selective NMDA receptor polyamine-site antagonist for studying excitotoxicity, synaptic plasticity, and long-term potentiation (LTP).
• Pharmacological Development: A key reference compound in the screening and development of novel neuroprotective agents and channel blockers.
• Biochemical Studies: Used to investigate the role of polyamines in receptor function and ion channel modulation.
• Cell Culture & In Vitro Models: Employed in experimental models of ischemic stroke, traumatic brain injury, and other neurological disorders.
• Standard & Reference Material: Serves as a high-purity analytical standard for quality control and method validation in related research.

Basic Information

Product Name	Arcaine
CAS No.	544-05-8
Molecular Formula	C6H16N6O2
Molecular Weight	204.23 g/mol
Synonyms	1,4-Diguanidinobutane; 1,4-Bis(guanyl)butane; Butane-1,4-diguanidine; Arcain; NSC 406130; Agmatine dimer; Bis(guanyl)butane
EINECS	208-861-8

Quality Control

Our Arcaine is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be provided to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.