Description

(2R,3R)-2,3,9,10-Tetrahydro-3,5-Dihydroxy-2-(4-Hydroxyphenyl)-8,8-Dimethyl-4H,8H-Benzo[1,2-B:3,4-B']Dipyran-4-One is a high-purity, optically active flavonoid derivative with significant biological activity. This compound is valued for its role as a key chiral intermediate and reference standard in advanced pharmaceutical research and development. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical, nutraceutical, and fine chemical sectors for applications requiring precise stereochemistry and high purity.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel therapeutic agents, particularly in cardiovascular and anti-inflammatory drug discovery.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in HPLC and LC-MS assays.
• Biochemical Research: Employed in studies investigating enzyme inhibition, antioxidant mechanisms, and structure-activity relationships (SAR) of flavonoid compounds.
• Nutraceutical Development: Acts as a premium-grade ingredient for advanced dietary supplements targeting oxidative stress, leveraging its natural flavonoid backbone.
• Cosmeceutical Actives: Incorporated into high-end skincare formulations for its potential antioxidant and skin-protective properties.
• Academic Research: Utilized in university and institutional labs for chemical synthesis projects and pharmacological studies.

Basic Information

Item	Detail
Product Name	(2R,3R)-2,3,9,10-Tetrahydro-3,5-Dihydroxy-2-(4-Hydroxyphenyl)-8,8-Dimethyl-4H,8H-Benzo[1,2-B:3,4-B']Dipyran-4-One
CAS No.	523-60-4
Molecular Formula	C20H18O6
Molecular Weight	354.35 g/mol
Synonyms	Taxifolin; Dihydroquercetin; (+)-Taxifolin; (2R,3R)-Dihydroquercetin; 3,5,7,3',4'-Pentahydroxyflavanone; Distylin; Larixine; Contact for details on additional trade names.
EINECS	208-333-9

Quality Control

Our (2R,3R)-2,3,9,10-Tetrahydro-3,5-Dihydroxy-2-(4-Hydroxyphenyl)-8,8-Dimethyl-4H,8H-Benzo[1,2-B:3,4-B']Dipyran-4-One is produced under strict quality management systems. Every batch is subjected to comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for research and manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% (2R,3R)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.