Description

Ellipticine is a naturally occurring alkaloid and a potent heterocyclic compound with significant biological activity. This molecule is of critical importance in pharmaceutical research and development due to its established role as a topoisomerase II inhibitor and intercalating agent. It is primarily sought after by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for the development of novel therapeutic agents and as a key reference standard in analytical studies.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold and active pharmaceutical ingredient (API) in the research and development of anticancer drugs.
• Biochemical Research: Used as a potent tool compound to study DNA intercalation mechanisms and topoisomerase II inhibition in cellular and molecular biology.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, and NMR for quality control and method validation in laboratories.
• Oncology Research: Investigated for its antitumor properties in preclinical studies targeting various cancer cell lines.
• Chemical Synthesis: Acts as a sophisticated building block for the synthetic modification and creation of novel derivatives with enhanced pharmacological profiles.

Basic Information

Product Name	Ellipticine
CAS No.	519-23-3
Molecular Formula	C17H14N2
Molecular Weight	246.31 g/mol
Synonyms	5,11-Dimethyl-6H-pyrido[4,3-b]carbazole; NSC 71795; 6H-Pyrido[4,3-b]carbazole, 5,11-dimethyl-; Ellipticine (base); Ellipticin; 9-Methoxyellipticine precursor
EINECS	Contact for details

Quality Control

Our Ellipticine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, and is supplied with a detailed Certificate of Analysis (COA). We support research and GMP-grade requirements, and specifications can be tailored to meet specific project needs upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.