Description

(3β,20α)-18β-Hydroxy-11,17α-Dimethoxyyohimban-16β-Carboxylic Acid 4-Oxide is a high-purity, complex indole alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate and reference standard for the synthesis and analytical study of bioactive molecules targeting neurological and cardiovascular systems. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers requiring precise, high-quality building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel therapeutic agents, particularly those derived from yohimbine alkaloids.
• Reference Standard: Used in analytical chemistry for method development, validation, and quality control (QC/QA) of related active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in pharmacological studies to investigate receptor binding activity and metabolic pathways.
• Fine Chemical Synthesis: A specialized building block for the custom synthesis of complex, high-value organic molecules for research purposes.

Basic Information

Product Name	(3β,20α)-18β-Hydroxy-11,17α-Dimethoxyyohimban-16β-Carboxylic Acid 4-Oxide
CAS No.	516-66-5
Molecular Formula	C22H26N2O7
Molecular Weight	430.45 g/mol
Synonyms	18-Hydroxy-11,17-dimethoxyyohimban-16-carboxylic acid 4-oxide; Yohimbine N-oxide derivative; 3β,20α-18β-Hydroxy-11,17α-dimethoxyyohimban-16β-carboxylic acid 4-oxide; 16β-Carboxy-18β-hydroxy-11,17α-dimethoxyyohimban 4-oxide; Ajmalicine derivative oxide; Raubasine related compound N-oxide; (3beta,20alpha)-18beta-Hydroxy-11,17alpha-dimethoxyyohimban-16beta-carboxylic acid 4-oxide
EINECS	Contact for details

Quality Control

Our (3β,20α)-18β-Hydroxy-11,17α-Dimethoxyyohimban-16β-Carboxylic Acid 4-Oxide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.