Description

6-β-Acetoxy-3-Beta(β-D-Glucopyranosyloxy)-8,14-Dihydroxybufa-4,20,22-Trienolide is a specialized cardiac glycoside derivative, a compound of significant interest in advanced pharmaceutical research and development. Its complex steroidal structure with a sugar moiety makes it a valuable reference standard and a key intermediate for synthesizing novel therapeutic agents. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors focusing on cardiovascular drug discovery and natural product chemistry.

Application

• Pharmaceutical Reference Standard: Serves as a certified analytical standard for quality control and method validation in drug manufacturing and regulatory compliance.
• Cardiovascular Drug Research: Used as a critical intermediate or lead compound in the research and development of new cardiac medications and inotropic agents.
• Biochemical Studies: Employed in pharmacological assays to study the mechanism of action of cardiac glycosides on sodium-potassium ATPase pumps.
• Natural Product Synthesis: Acts as a sophisticated building block for the semi-synthesis or total synthesis of complex bufadienolide and cardenolide analogs.
• Academic & Institutional Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) within the steroid glycoside class.

Basic Information

Item	Detail
Product Name	6-β-Acetoxy-3-Beta(β-D-Glucopyranosyloxy)-8,14-Dihydroxybufa-4,20,22-Trienolide
CAS No.	507-60-8
Molecular Formula	C32H44O12
Molecular Weight	620.69 g/mol
Synonyms	6β-Acetoxy-3β-(β-D-glucopyranosyloxy)-8,14-dihydroxybufa-4,20,22-trienolide; Bufalin 3-O-β-D-glucoside, 6-acetate; Gamabufotalin 3-O-β-D-glucoside acetate; 3-[(6-O-Acetyl-β-D-glucopyranosyl)oxy]-6,8,14-trihydroxybufa-4,20,22-trienolide; 6-Acetyl Gamabufotalin glucoside; Bufadienolide glycoside derivative; Cardiac glycoside intermediate; Reference Standard 507-60-8
EINECS	Contact for details

Quality Control

Our 6-β-Acetoxy-3-Beta(β-D-Glucopyranosyloxy)-8,14-Dihydroxybufa-4,20,22-Trienolide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS, IR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.