Description

Dl-Penicillamine CAS NO 52-66-4 is a synthetic, sulfur-containing amino acid derivative and a chelating agent. It is a critical pharmaceutical intermediate and active ingredient, valued for its ability to bind to and remove heavy metals from the body. This compound is essential for manufacturers in the pharmaceutical industry, particularly for the production of chelation therapies and as a key starting material in advanced drug synthesis.

Application

• Pharmaceutical Active Ingredient: Primarily used as a chelating agent in the treatment of Wilson's disease, cystinuria, and rheumatoid arthritis.
• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of more complex drug molecules and APIs (Active Pharmaceutical Ingredients).
• Research & Development: Utilized in biochemical and pharmacological research for studying metal-protein interactions and chelation mechanisms.
• Veterinary Medicine: Applied in formulations for the treatment of copper toxicity in animals.
• Chemical Synthesis: Acts as a chiral ligand or catalyst in asymmetric synthesis and other specialized organic reactions.

Basic Information

Product Name	Dl-Penicillamine
CAS No.	52-66-4
Molecular Formula	C5H11NO2S
Molecular Weight	149.21 g/mol
Synonyms	D-Penicillamine; L-Penicillamine (racemic mixture); 3-Mercapto-D-valine; β,β-Dimethylcysteine; 3,3-Dimethyl-D-cysteine; Cuprimine (brand name); Depen (brand name); Mercaptyl
EINECS	200-148-8

Quality Control

Our Dl-Penicillamine is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We can supply material compliant with various pharmacopoeial standards, including USP and EP, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider an inert atmosphere. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0%
Specific Rotation	-60.0° to -63.0° (c=1, 1N NaOH)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.