Description

4H-1,3-Benzodioxine-7-Sulfonyl Chloride, 97% is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its reactive sulfonyl chloride group makes it an essential reagent for introducing the benzodioxine sulfonyl moiety into target molecules, enabling the creation of complex chemical architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting the central nervous system or requiring specific sulfonamide functionalities.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the benzodioxine scaffold can contribute to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probe Development: Employed to create sulfonamide-based probes for studying enzyme activity and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences.

Basic Information

Item	Detail
Product Name	4H-1,3-Benzodioxine-7-Sulfonyl Chloride, 97%
CAS No.	499771-01-6
Molecular Formula	C8H5ClO4S
Molecular Weight	232.64 g/mol
Synonyms	7-(Chlorosulfonyl)-4H-1,3-benzodioxine; 4H-1,3-Benzodioxine-7-sulfonyl chloride; 1,3-Benzodioxine-7-sulfonyl chloride, 4H-; Benzodioxine sulfonyl chloride; 7-Chlorosulfonyl-4H-benzo[1,3]dioxine
EINECS	Contact for details

Quality Control

Our 4H-1,3-Benzodioxine-7-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.