Description

2,3-Dihydro-1,4-Benzodioxine-2-Sulfonyl Chloride, 97% is a high-purity sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile electrophile for introducing the 1,4-benzodioxine sulfonyl moiety, a privileged scaffold in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors, receptor antagonists, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the benzodioxine structure can contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Can be utilized as a reactive handle for bioconjugation or as a precursor for activity-based probes in biochemical research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,3-Dihydro-1,4-Benzodioxine-2-Sulfonyl Chloride, 97%
CAS No.	499770-80-8
Molecular Formula	C8H7ClO4S
Molecular Weight	234.66 g/mol
Synonyms	1,4-Benzodioxine-2-sulfonyl chloride, 2,3-dihydro-; 2,3-Dihydro-1,4-benzodioxin-2-sulfonyl chloride; 2-Sulfonylchloride-2,3-dihydro-1,4-benzodioxine; 1,4-Benzodioxane-2-sulfonyl chloride (common misnomer); 2,3-Dihydrobenzo[b][1,4]dioxine-2-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1,4-Benzodioxine-2-Sulfonyl Chloride, 97% is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency meet the specified standard. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.