Description

2-Propanamine,1-[(4-Fluoro-3-Pyridinyl)Oxy]-N,n-Dimethyl-,(2R)-(9Ci) is a high-purity, chiral amine derivative with a fluoropyridinyloxy substituent, serving as a critical advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of complex, biologically active molecules with high stereochemical fidelity, which is essential for modern drug discovery and development. This compound is primarily needed by research institutions and pharmaceutical manufacturers focused on creating novel therapeutic agents, particularly in areas requiring specific enantiomeric control.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) with specific stereochemistry.
• Agrochemical Research: Used in the development of advanced crop protection agents and herbicides.
• Ligand Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and the creation of targeted molecular libraries.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring the introduction of a fluorinated pyridine moiety.
• Bioconjugation: Potential use in linking molecules for diagnostic or therapeutic purposes.

Basic Information

Item	Details
Product Name	2-Propanamine,1-[(4-Fluoro-3-Pyridinyl)Oxy]-N,n-Dimethyl-,(2R)-(9Ci)
CAS No.	497948-95-5
Molecular Formula	C10H15FN2O
Molecular Weight	198.24 g/mol
Synonyms	(2R)-1-[(4-Fluoro-3-pyridinyl)oxy]-N,N-dimethyl-2-propanamine; (R)-1-((4-Fluoro-3-pyridinyl)oxy)-N,N-dimethyl-2-propanamine; (R)-N,N-Dimethyl-1-((4-fluoro-3-pyridyl)oxy)propan-2-amine; 1-[(4-Fluoro-3-pyridinyl)oxy]-N,N-dimethyl-(2R)-2-propanamine; (R)-1-(4-Fluoro-3-pyridyloxy)-N,N-dimethylisopropylamine; Fluoropyridine propanamine derivative; Chiral fluoropyridinyloxy amine
EINECS	Contact for details

Quality Control

Our production of 2-Propanamine,1-[(4-Fluoro-3-Pyridinyl)Oxy]-N,n-Dimethyl-,(2R)-(9Ci) adheres to stringent quality management systems, ensuring batch-to-batch consistency for research and development applications. The material undergoes rigorous analytical testing, including chiral purity verification by HPLC and identity confirmation by NMR and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.