Description

8-Fluoroquinoline-4-Carbaldehyde is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a reactive aldehyde group and a fluorine-substituted quinoline scaffold, enabling precise molecular construction for high-value applications. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluorinated quinolone-based drug candidates, including potential antibiotics and anticancer agents.
• Agrochemical Research: Used to develop new fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for catalysis or components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: The reactive aldehyde group facilitates condensation and cyclization reactions to construct complex heterocyclic systems for various research purposes.
• Fluorine Chemistry Studies: An important substrate for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in medicinal chemistry.

Basic Information

Product Name	8-Fluoroquinoline-4-Carbaldehyde
CAS No.	496792-30-4
Molecular Formula	C10H6FNO
Molecular Weight	175.16 g/mol
Synonyms	4-Quinolinecarboxaldehyde, 8-fluoro-; 8-Fluoro-4-quinolinecarboxaldehyde; 8-Fluoroquinoline-4-carboxaldehyde; 8-Fluoro-4-formylquinoline; 8-Fluoro-4-quinolinealdehyde; 496792-30-4; 8-Fluoro-4-quinolylcarboxaldehyde
EINECS	Contact for details

Quality Control

Our 8-Fluoroquinoline-4-Carbaldehyde is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This compound is easily oxidized; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.