Description

Thiohomosildenafil is a synthetic organic compound belonging to the class of phosphodiesterase type 5 (PDE5) inhibitors. This compound is of significant interest in pharmaceutical research and development for its structural and functional properties. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and related intermediates.

Application

• Pharmaceutical Research Intermediate: Serves as a key synthetic precursor or analog in the development of novel PDE5 inhibitor compounds.
• Biochemical Research: Used in in vitro studies to investigate enzyme inhibition mechanisms and structure-activity relationships (SAR).
• Reference Standard: Employed as an analytical standard for quality control and method development in analytical laboratories.
• Chemical Synthesis: Acts as a building block for the synthesis of more complex molecular entities in medicinal chemistry programs.

Basic Information

Product Name	Thiohomosildenafil
CAS No.	479073-80-8
Molecular Formula	C22H30N6O3S
Molecular Weight	458.58 g/mol
Synonyms	Thiohomosildenafil; 5-[2-Ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one; Homosildenafil thio analog; PDE5 inhibitor analog
EINECS	Contact for details

Quality Control

Our Thiohomosildenafil is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.