Description

[1,2-13C2]Glycolaldehyde is a stable isotope-labeled analog of glycolaldehyde, where both carbon atoms are enriched with the carbon-13 isotope. This compound is a critical tool for advanced research, enabling precise metabolic pathway tracing and structural elucidation in complex biochemical systems through techniques like NMR spectroscopy and mass spectrometry. It is essential for scientists in pharmaceutical development, metabolic research, and analytical chemistry who require high-fidelity isotopic labels for accurate data generation.

Application

• Metabolic Flux Analysis (MFA): Used as a 13C-labeled tracer to study central carbon metabolism, glycolysis, and the pentose phosphate pathway in cells and microorganisms.
• Drug Metabolism and Pharmacokinetics (DMPK): Serves as an internal standard or precursor in the synthesis of labeled drug metabolites for quantitative LC-MS/MS analysis.
• NMR Spectroscopy: Provides a distinct 13C NMR signal for investigating reaction mechanisms, protein-ligand interactions, and the structure of complex carbohydrates.
• Biochemical Research: A key building block in the study of advanced glycation end-products (AGEs) and non-enzymatic glycosylation reactions under isotopically enriched conditions.
• Stable Isotope Labeling: Employed in the synthesis of more complex 13C-labeled compounds for use as diagnostic probes or research chemicals.

Basic Information

Product Name	[1,2-13C2]Glycolaldehyde
CAS No.	478529-69-0
Molecular Formula	13C2H4O2
Molecular Weight	62.04 (for 13C2 labeled form)
Synonyms	1,2-13C2-Glycolaldehyde; [1,2-13C]Glycolaldehyde; 2-Hydroxy[1,2-13C2]acetaldehyde; Hydroxyacetaldehyde-13C2; Glycolic aldehyde-13C2; (1,2-13C)Hydroxyethanal; Stable Isotope Labeled Glycolaldehyde
EINECS	Contact for details

Quality Control

Every batch of [1,2-13C2]Glycolaldehyde is produced and analyzed under strict quality protocols to ensure isotopic and chemical purity for research applications. Our products undergo rigorous quality testing, including isotopic enrichment analysis by NMR and LC-MS, to ensure compliance with exacting research standards. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and solvent content is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid or solution
Identification (NMR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98%
Isotopic Purity (MS)	≥ 99% 13C2

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.