Description

D-[1,2,3,3'-2H4]Glyceraldehyde is a stable isotope-labeled derivative of the fundamental triose sugar, glyceraldehyde, where four hydrogen atoms are replaced with deuterium. This high-purity labeled compound is essential for advanced research requiring precise metabolic and enzymatic pathway tracing. It is primarily utilized by scientists in pharmaceutical R&D, biochemistry, and analytical chemistry for applications such as NMR spectroscopy, mass spectrometry, and isotope dilution studies.

Application

• Metabolic Pathway Analysis: Used as a deuterated tracer to study glycolysis, gluconeogenesis, and the pentose phosphate pathway in biological systems.
• Biochemical Research: Serves as a key intermediate in enzymatic studies and the synthesis of labeled complex carbohydrates and nucleotides.
• Analytical Chemistry Standards: Employed as an internal standard in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy for accurate quantification.
• Pharmaceutical Development: Facilitates drug metabolism and pharmacokinetics (DMPK) studies by tracking the incorporation of labeled fragments into active pharmaceutical ingredients (APIs).
• Isotope Labeling Synthesis: Acts as a crucial building block for the preparation of more complex deuterium-labeled organic molecules and biomolecules.

Basic Information

Product Name	D-[1,2,3,3'-2H4]Glyceraldehyde
CAS No.	478529-60-1
Molecular Formula	C3H2D4O3
Molecular Weight	94.10 g/mol
Synonyms	(2R)-2,3-Dihydroxy-1,1,2,3-tetradeuteriopropanal; D-Glyceraldehyde-1,1,2,3-d4; Deuterated D-Glyceraldehyde; [1,2,3,3'-2H4]-D-Glyceraldehyde; (R)-Glyceraldehyde-d4; 2,3-Dihydroxypropanal-d4; D-Glyceraldehyde-d4
EINECS	Contact for details

Quality Control

Every batch of D-[1,2,3,3'-2H4]Glyceraldehyde is produced and analyzed under strict quality protocols to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment (D, atom %), chemical purity, and specific analytical data from NMR, MS, and HPLC are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Isotopic Purity (D, atom %)	≥ 98%
Chemical Purity (HPLC)	≥ 95%
Specific Rotation	Contact for details
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.