Description

2-[15N]Acetamido-2-Deoxy-D-[Ul-13C6]Glucose is a highly specialized, isotopically labeled derivative of N-acetylglucosamine, a fundamental building block in glycobiology and metabolic research. This compound, with CAS number 478529-41-8, is critical for advanced analytical applications requiring precise tracking and quantification of metabolic pathways. It is primarily utilized by research scientists and process developers in pharmaceutical R&D, academic institutions, and diagnostic development labs. Its unique labeling pattern enables unparalleled insights into glycosylation processes and carbohydrate metabolism.

Application

• Metabolic Flux Analysis (MFA): Used as a stable isotope-labeled tracer to map and quantify intracellular metabolic pathways in cell culture and microbiological studies.
• Glycoprotein & Glycolipid Research: Serves as a biosynthetic precursor for the study of N-linked and O-linked glycosylation, aiding in the understanding of protein function and cell signaling.
• Pharmaceutical Development: Employed in the research and development of glycosidase inhibitors, anti-cancer agents, and anti-inflammatory drugs that target carbohydrate-mediated processes.
• Biomarker Discovery & Diagnostics: Utilized in mass spectrometry-based proteomics and metabolomics for the accurate identification and quantification of disease-specific glycans.
• NMR Spectroscopy: Acts as a standard or internal reference in nuclear magnetic resonance studies due to its 13C and 15N enrichment, simplifying spectral interpretation.
• Enzyme Kinetics Studies: Applied in assays to investigate the mechanism and inhibition of enzymes like hexokinase and glycosyltransferases.

Basic Information

Product Name	2-[15N]Acetamido-2-Deoxy-D-[Ul-13C6]Glucose
CAS No.	478529-41-8
Molecular Formula	C813C6H1515NO6
Molecular Weight	~227.18 (for 13C6, 15N labeled form)
Synonyms	N-Acetyl-D-[U-13C6]glucosamine-15N; [U-13C6, 15N]-NAG; 2-Acetamido-2-deoxy-D-[U-13C6]glucose-15N; Isotopically Labeled N-Acetylglucosamine; 13C6,15N-GlcNAc; 2-(15N)Acetamido-2-deoxy-D-glucose-13C6; N-Acetyl-15N, [U-13C6]-D-glucosamine
EINECS	Contact for details

Quality Control

Every batch of 2-[15N]Acetamido-2-Deoxy-D-[Ul-13C6]Glucose is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing via NMR, HPLC, and Mass Spectrometry to confirm identity, assay, and isotopic enrichment. Certificates of Analysis (COA) detailing batch-specific results for purity, isotopic abundance, and solvent residues are provided with every shipment. Our quality commitment ensures reliability for your most sensitive research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or with desiccant to maintain stability and prevent decomposition. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Isotopic Enrichment (15N)	≥ 98 atom % 15N
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.