Description

Tri-o-Acetyl-D-[2-13C]Glucal is a stable isotope-labeled derivative of glucal, specifically enriched with carbon-13 at the C-2 position and fully acetylated. This compound is a crucial advanced synthetic intermediate and tracer molecule for research in carbohydrate chemistry and metabolic studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and specialty chemical manufacturers for the development of labeled glycosides, nucleosides, and other bioactive molecules.

Application

• Isotope-Labeled Synthesis: A key building block for the synthesis of carbon-13 labeled carbohydrates, nucleosides, and glycoconjugates for metabolic pathway tracing.
• Pharmaceutical Research: Used in the development and mechanistic study of glycosidase inhibitors, antiviral agents, and other therapeutics targeting carbohydrate-processing enzymes.
• NMR Spectroscopy: Serves as a valuable precursor for preparing isotopically enriched standards for Nuclear Magnetic Resonance (NMR) analysis, enhancing signal detection and structural elucidation.
• Glycobiology Studies: Enables the investigation of glycosylation processes, enzyme mechanisms, and carbohydrate-protein interactions in labeled form.
• Chemical Biology Probes: Facilitates the creation of tagged molecular probes to study biological recognition and signaling events involving sugars.
• Process Chemistry Development: Acts as a specialized intermediate for optimizing synthetic routes to complex, labeled natural products and active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	Tri-o-Acetyl-D-[2-13C]Glucal
CAS No.	478529-36-1
Molecular Formula	C12H1613CO8
Molecular Weight	~289.25 g/mol
Synonyms	1,5-Anhydro-2-deoxy-D-arabino-hex-1-enitol 3,4,6-Triacetate-2-13C; D-Glucal Triacetate-2-13C; (2R,3S,4R,5R)-3,4,5-Tris(acetyloxy)-6-(hydroxymethyl)-3,4-dihydro-2H-pyran-2-13C; Tri-O-acetyl-2-13C-D-glucal; 3,4,6-Tri-O-acetyl-1,5-anhydro-2-deoxy-D-arabino-hex-1-enitol-2-13C; [2-13C]-Tri-O-acetyl-D-glucal
EINECS	Contact for details

Quality Control

Our Tri-o-Acetyl-D-[2-13C]Glucal is produced under strict quality management protocols to ensure high isotopic and chemical purity. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry to verify isotopic enrichment, chemical identity, and purity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and kept in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.