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6-Deoxy-L-[3-13C]Galactose CAS NO 478518-50-2


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CAS No.:478518-50-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Deoxy-L-[3-13C]Galactose is a stable isotope-labeled derivative of the monosaccharide 6-deoxy-L-galactose (L-fucose), specifically enriched with carbon-13 at the C-3 position. This compound is a critical tool for advanced metabolic research and tracer studies, providing unparalleled specificity for tracking biochemical pathways via techniques like NMR spectroscopy and mass spectrometry. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity, isotopically labeled standards for metabolic flux analysis, drug development, and biomarker discovery.

Application

  • Metabolic Tracer Studies: Used in 13C-NMR and GC/MS analyses to elucidate metabolic pathways and flux in biological systems.
  • Pharmaceutical Research: Serves as a labeled precursor in the development and testing of novel therapeutics, particularly those targeting glycosylation processes or carbohydrate metabolism.
  • Glycobiology Research: Essential for studying fucose metabolism, fucosylation of glycoproteins and glycolipids, and related cellular communication processes.
  • Diagnostic Agent Development: Employed in the synthesis of advanced contrast agents or probes for molecular imaging (e.g., PET, if further labeled with 18F).
  • Biochemical Standard: Acts as a high-purity internal standard for quantitative mass spectrometry, ensuring accuracy in complex biological sample analysis.
  • Enzymology Studies: Utilized to investigate the kinetics and mechanisms of enzymes involved in L-fucose metabolism, such as fucosyltransferases.

Basic Information

Product Name 6-Deoxy-L-[3-13C]Galactose
CAS No. 478518-50-2
Molecular Formula C513CH12O5
Molecular Weight 165.15 g/mol (for 13C1 labeled)
Synonyms L-[3-13C]Fucose; 6-Deoxy-L-[3-13C]galactose; (3-13C)-6-Deoxy-L-galactose; L-(-)-Fucose-3-13C; Isotopically labeled L-fucose; 6-Deoxy-L-galactose-3-13C; [3-13C]-L-Fucose
EINECS Contact for details

Quality Control

Every batch of 6-Deoxy-L-[3-13C]Galactose is manufactured and analyzed under strict quality systems to ensure exceptional isotopic and chemical purity for research applications. Our quality commitment includes comprehensive testing via NMR, HPLC, and MS to verify isotopic enrichment, chemical identity, and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for isotopic purity, chemical purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere or in a desiccator to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (NMR) Conforms to structure
Isotopic Purity (13C) ≥ 99 atom % 13C
Chemical Purity (HPLC) ≥ 98%
Specific Optical Rotation Contact for details
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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