Description

[1'-13C]2'-Deoxycytidine Monohydrate is a stable isotope-labeled nucleoside derivative, specifically a monohydrate form of 2'-deoxycytidine with a carbon-13 label at the 1' position of the sugar moiety. This precise isotopic labeling is critical for advanced research applications requiring high sensitivity and specificity in detection and quantification. It is an essential biochemical tool for scientists in pharmaceutical development, metabolic research, and analytical chemistry.

Application

• Isotope Tracer Studies: Used as a labeled precursor in metabolic flux analysis and pharmacokinetic studies to track the incorporation and fate of nucleosides.
• Mass Spectrometry Standards: Serves as an internal standard for the accurate quantification of endogenous 2'-deoxycytidine and related metabolites via LC-MS/MS and GC-MS.
• Nucleic Acid Research: Employed in the synthesis of isotopically labeled oligonucleotides for structural NMR studies and mechanistic investigations of DNA/RNA-protein interactions.
• Drug Discovery & Development: Aids in the study of nucleoside analog drugs, helping to elucidate metabolic pathways, mechanisms of action, and potential drug-drug interactions.
• Biomedical Diagnostics: Can be utilized in developing advanced diagnostic assays for conditions related to nucleotide metabolism imbalances.

Basic Information

Product Name	[1'-13C]2'-Deoxycytidine Monohydrate
CAS No.	478510-83-7
Molecular Formula	C913CH15N3O5 • H2O
Molecular Weight	263.23 g/mol (for 13C1 labeled form)
Synonyms	1'-Carbon-13 Labeled 2'-Deoxycytidine Monohydrate; [1'-13C]dC Monohydrate; 1'-13C-2'-Deoxycytidine Hydrate; 4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-1-13C-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Monohydrate; Cytosine Deoxyriboside-1'-13C Monohydrate; Labeled Deoxycytidine; Isotopic Nucleoside Standard
EINECS	Contact for details

Quality Control

Every batch of [1'-13C]2'-Deoxycytidine Monohydrate is produced and analyzed under strict quality systems. We ensure high isotopic and chemical purity through advanced analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) are provided with each shipment, detailing batch-specific results for identity, purity, isotopic enrichment, and water content.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Keep container sealed under inert atmosphere when not in use to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Water Content (KF)	4.0 - 7.0 %
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.