Description

D-[Ul-13C5]Xylose is a stable isotope-labeled analog of the pentose sugar D-xylose, where five carbon atoms are uniformly labeled with the carbon-13 isotope. This compound is essential for advanced metabolic and pharmacokinetic studies, providing a precise tracer for quantitative analysis via mass spectrometry and NMR spectroscopy. It is primarily used by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications requiring high isotopic purity and chemical stability.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to study central carbon metabolism pathways in microbial, plant, and mammalian cell cultures.
• Drug Metabolism and Pharmacokinetics (DMPK): Serves as an internal standard for the accurate quantification of D-xylose and related metabolites in bioanalytical assays.
• Clinical Research Diagnostics: Employed in the development of stable isotope dilution assays for gastrointestinal function tests and carbohydrate malabsorption studies.
• Biomolecular NMR Spectroscopy: Provides a non-radioactive, enriched probe for structural and dynamic studies of carbohydrate-binding proteins and enzymes.
• Nutritional Science Research: Facilitates the investigation of dietary xylose uptake, utilization, and its role in gut microbiome metabolism.
• Isotope-Labeled Reference Standard: Acts a certified reference material (CRM) for quality control and method validation in analytical laboratories.

Basic Information

Product Name	D-[Ul-13C5]Xylose
CAS No.	478506-58-0
Molecular Formula	¹³C₅H₁₀O₅
Molecular Weight	155.08 g/mol (for ¹³C₅)
Synonyms	D-(+)-Xylose-¹³C₅; D-Xylose (U-¹³C₅); (2R,3S,4R)-2,3,4,5-Tetrahydroxypentanal-¹³C₅; Aldopentose-¹³C₅; Wood Sugar-¹³C₅; Stable Isotope Labeled D-Xylose; ¹³C₅-Xylose; [U-¹³C]Xylose
EINECS	Contact for details

Quality Control

Our D-[Ul-13C5]Xylose is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (Atom % ¹³C), chemical purity by HPLC, and specific optical rotation. We support research and production needs compliant with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, consider sealing under argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % ¹³C)	≥ 99%
Specific Optical Rotation	+18.5° to +19.5° (c=10 in H₂O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.