Description

Mif Antagonist, iso-1 CAS NO 478336-92-4 is a high-purity, small molecule compound designed as a potent and selective antagonist of the macrophage migration inhibitory factor (MIF) receptor, isoform 1. This compound is critical for advanced research into inflammatory pathways, autoimmune disorders, and oncology, where MIF signaling plays a key regulatory role. It is an essential tool for pharmaceutical R&D, academic research institutions, and biotechnology companies focused on developing novel therapeutic interventions.

Application

• Pharmacological Research: Used as a key reference standard and active agent in studies investigating the role of MIF in inflammatory and autoimmune diseases.
• Drug Discovery & Development: Serves as a lead compound or a critical intermediate in the synthesis and screening of new MIF-targeted therapeutics.
• Biochemical Assays: Employed in in vitro and cell-based assays to study receptor binding affinity, signal transduction inhibition, and downstream cellular effects.
• Oncology Research: Utilized to explore the contribution of MIF to tumor progression, angiogenesis, and immune evasion within the tumor microenvironment.
• Academic & Institutional Studies: A vital reagent for fundamental research into cytokine biology and the development of experimental disease models.

Basic Information

Product Name	Mif Antagonist, iso-1
CAS No.	478336-92-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MIF Antagonist iso-1; ISO-1 MIF Inhibitor; (S,R)-3-(4-Hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid methyl ester; MIF Signaling Inhibitor; Macrophage Migration Inhibitory Factor Antagonist; 4-IPP analog; CXCR7/ACKR3 ligand; Small Molecule MIF Antagonist
EINECS	Contact for details

Quality Control

Our Mif Antagonist, iso-1 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product at -20°C under desiccant.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.