Description

Ethyl 4-(3,4-Difluorophenyl)-2-Methyl-6-Oxo-1,4,5,6-Tetrahydro-3-Pyridinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific dihydropyridine core structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting cardiovascular and neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Synthesis: Serves as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Academic & Institutional Research: Utilized in university and research institute laboratories for pharmacological and biochemical studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	Ethyl 4-(3,4-Difluorophenyl)-2-Methyl-6-Oxo-1,4,5,6-Tetrahydro-3-Pyridinecarboxylate
CAS No.	478261-60-8
Molecular Formula	C15H15F2NO3
Molecular Weight	295.28 g/mol
Synonyms	Ethyl 4-(3,4-difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxylate; 1,4-Dihydro-2-methyl-4-(3,4-difluorophenyl)-6-oxo-3,5-pyridinedicarboxylic acid 3-ethyl ester; 3-Carbethoxy-4-(3,4-difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine; 478261-60-8; 4-(3,4-Difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxylic acid ethyl ester; Ethyl 4-(3,4-difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of Ethyl 4-(3,4-Difluorophenyl)-2-Methyl-6-Oxo-1,4,5,6-Tetrahydro-3-Pyridinecarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.