Description

Cathepsin L Inhibitor Vi is a potent and selective small-molecule inhibitor of the cysteine protease Cathepsin L. This compound is a critical research tool for investigating the role of Cathepsin L in various physiological and pathological processes, including cancer metastasis, viral entry, and bone resorption. It is essential for pharmaceutical R&D, academic research, and biotechnology applications focused on protease biology and therapeutic target validation.

Application

• Biomedical Research: Used as a key pharmacological probe to study the specific functions of Cathepsin L in cell culture and animal models.
• Drug Discovery & Development: Serves as a reference compound and a starting point for the design of novel therapeutic agents targeting Cathepsin L in oncology, virology, and inflammatory diseases.
• Mechanistic Studies: Employed to elucidate the pathways involving Cathepsin L in protein degradation, antigen presentation, and extracellular matrix remodeling.
• Biochemical Assay Development: Utilized as a standard inhibitor in high-throughput screening (HTS) and enzymatic assays to identify and characterize new Cathepsin L inhibitors.
• Academic & Institutional Research: Fundamental tool for universities and research institutes exploring protease biology, cancer biology, and infectious disease mechanisms.

Basic Information

Product Name	Cathepsin L Inhibitor Vi
CAS No.	478164-48-6
Molecular Formula	C20H20N4O3S
Molecular Weight	396.46 g/mol
Synonyms	Z-FY(t-Bu)-DMK; (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-4-Methyl-1-[[(2S)-1-oxo-3-phenyl-1-[[(2,2,2-trifluoroacetyl)amino]propan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-(5-methyl-2-furanyl)-4-thiazolecarboxamide; Cathepsin L Inhibitor VI; Z-FY(tBu)-diazomethylketone; Z-FY(t-Bu)-CHN2
EINECS	Contact for details

Quality Control

Our Cathepsin L Inhibitor Vi is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, NMR and MS for structural confirmation, and identity tests. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with desiccant to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.