Description

3-(Chloromethyl)-2-Fluoropyridine Hydrochloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its molecular architecture, featuring both a reactive chloromethyl group and a fluorine substituent on the pyridine ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A valuable scaffold for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-(Chloromethyl)-2-Fluoropyridine Hydrochloride
CAS No.	477207-34-4
Molecular Formula	C6H6Cl2FN
Molecular Weight	182.02 g/mol
Synonyms	2-Fluoro-3-(chloromethyl)pyridine hydrochloride; 3-(Chloromethyl)-2-fluoropyridine HCl; 2-Fluoro-3-pyridinemethanol, chloromethyl-, hydrochloride; (2-Fluoro-3-pyridinyl)methyl chloride hydrochloride; 2-Fluoro-3-chloromethylpyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)-2-Fluoropyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.