Description

[U-Ring-13C6]-4-Chlorophenol is a stable isotope-labeled internal standard, specifically a uniformly 13C6-labeled derivative of 4-chlorophenol. This compound is essential for ensuring the accuracy and reliability of quantitative analyses in sophisticated mass spectrometry-based methods. It is a critical reagent for researchers and quality control laboratories in the pharmaceutical, environmental monitoring, and agrochemical sectors who require precise quantification of 4-chlorophenol and related compounds.

Application

• Quantitative Mass Spectrometry: Serves as an internal standard for the precise quantification of 4-chlorophenol in LC-MS/MS and GC-MS analyses, correcting for instrument variability and sample preparation losses.
• Pharmaceutical Impurity Profiling: Used in method development and validation to track and quantify chlorophenol-related impurities or degradation products in active pharmaceutical ingredients (APIs) and drug formulations.
• Environmental Analysis: Enables accurate measurement of 4-chlorophenol, a pollutant and degradation product of certain herbicides and fungicides, in water, soil, and biological samples.
• Metabolite Studies: Facilitates the detection and quantification of 4-chlorophenol metabolites in pharmacokinetic and toxicological research.
• Method Validation & Compliance: Supports analytical method validation in compliance with regulatory guidelines (e.g., FDA, EMA, ICH Q2(R1)) for robustness, accuracy, and precision.
• Dioxin & PCB Analysis: Applied in related environmental testing protocols where chlorophenols are precursors or markers.

Basic Information

Product Name	[U-Ring-13C6]-4-Chlorophenol
CAS No.	475295-86-4
Molecular Formula	C613C6H5ClO
Molecular Weight	~135.53 (for 13C6 labeled core)
Synonyms	4-Chlorophenol-13C6; 4-Chloro-13C6-phenol; Uniformly 13C-labeled 4-Chlorophenol; p-Chlorophenol-13C6; 4-CP-13C6; 1-Chloro-4-hydroxybenzene-13C6; Isotopic Internal Standard 475295-86-4
EINECS	Contact for details

Quality Control

Every batch of [U-Ring-13C6]-4-Chlorophenol is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity as verified by NMR (Nuclear Magnetic Resonance) and mass spectrometry. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific purity, isotopic enrichment, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C for long-term stability. The product is light-sensitive and should be handled under appropriate conditions to maintain its integrity as a quantitative standard.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98% (chemical purity)
Isotopic Enrichment	≥99 atom % 13C
Isotopic Purity (MS)	≥98% (M+6)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.