Description

7-Trifluoromethyl-[1,2,4]Triazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-value heterocyclic building block featuring a fused triazolopyrimidine core with a carboxylic acid and a trifluoromethyl group. This compound matters for its role as a key synthetic intermediate in the development of advanced pharmaceuticals and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the triazolopyrimidine scaffold.
• Chemical Research & Development: Serves as a versatile precursor for constructing complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science: Potential intermediate for the synthesis of specialty polymers or organic electronic materials due to its rigid, functionalized structure.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	7-Trifluoromethyl-[1,2,4]Triazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	473994-56-8
Molecular Formula	C7H3F3N4O2
Molecular Weight	232.12 g/mol
Synonyms	7-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acid; 7-Trifluoromethyl-1,2,4-triazolo[1,5-a]pyrimidine-2-carboxylic Acid; 2-Carboxy-7-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyrimidine; 473994-56-8; 7-Trifluoromethyltriazolopyrimidine-2-carboxylic acid; TTPCA; 7-CF3-Triazolopyrimidine-2-COOH
EINECS	Contact for details

Quality Control

Our production of 7-Trifluoromethyl-[1,2,4]Triazolo[1,5-A]Pyrimidine-2-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support development and commercial projects with material that meets the rigorous standards required for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.