Description

(±)-NBI 74330 is a high-purity chemical compound, identified by CAS number 473722-68-8, that serves as a critical research-grade biochemical tool. This compound is valued for its specific activity as a potent and selective antagonist, enabling advanced pharmacological and neurological studies. It is primarily required by research institutions and pharmaceutical developers engaged in neuroscience, receptor characterization, and the discovery of novel therapeutic agents.

Application

• Neuroscience Research: Used as a selective pharmacological tool to study receptor function and signaling pathways in the central nervous system.
• Drug Discovery & Development: Serves as a reference standard and lead compound in the screening and development of new therapeutic agents targeting specific receptors.
• Biochemical Assays: Employed in in vitro binding and functional assays to determine receptor affinity, potency, and mechanism of action.
• Academic & Institutional Research: Facilitates fundamental research in universities and laboratories focused on neuropharmacology and cellular physiology.
• Preclinical Studies: Utilized in animal model studies to investigate the physiological and behavioral effects of receptor modulation.

Basic Information

Product Name	(±)-NBI 74330
CAS No.	473722-68-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NBI-74330; NBI 74330; 2-Methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine; CRF1 Receptor Antagonist NBI-74330; Corticotropin-Releasing Factor Receptor 1 Antagonist
EINECS	Contact for details

Quality Control

Our (±)-NBI 74330 is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all quality parameters is provided with every shipment to support your research integrity and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under controlled conditions to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.