Description

3'-Trifluoromethoxy-Biphenyl-4-Carbaldehyde is a high-purity aromatic aldehyde building block featuring a biphenyl core substituted with a trifluoromethoxy group. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, where its unique electronic and steric properties are leveraged. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammation.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An effective substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Organic Ligand Preparation: Utilized for the synthesis of specialized ligands used in catalysis and material science.
• Chemical Research & Development: A valuable building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3'-Trifluoromethoxy-Biphenyl-4-Carbaldehyde
CAS No.	473257-33-9
Molecular Formula	C14H9F3O2
Molecular Weight	266.22 g/mol
Synonyms	4-Formyl-3'-(trifluoromethoxy)biphenyl; [1,1'-Biphenyl]-4-carboxaldehyde, 3'-(trifluoromethoxy)-; 3'-(Trifluoromethoxy)[1,1'-biphenyl]-4-carbaldehyde; 3'-Trifluoromethoxy-4-formylbiphenyl; 4-Biphenylcarboxaldehyde, 3'-trifluoromethoxy-; 3'-Trifluoromethoxybiphenyl-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 3'-Trifluoromethoxy-Biphenyl-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.