Description

2-Chloro-5-(Trifluoromethoxy)Benzaldehyde is a versatile and high-value aromatic aldehyde building block, distinguished by its unique combination of chloro and trifluoromethoxy substituents. This compound is critical for synthesizing advanced intermediates where electronic and steric properties must be precisely tuned. It is primarily sought after by research institutions and manufacturers in the agrochemical and pharmaceutical sectors for developing novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the stability and lipophilicity imparted by the trifluoromethoxy group.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of active pharmaceutical ingredients (APIs), particularly in scaffolds requiring halogenated aromatic systems.
• Liquid Crystal & OLED Material Synthesis: Serves as a starting material for creating advanced organic electronic compounds and liquid crystal molecules.
• Functional Dye & Pigment Production: Employed in the synthesis of specialized dyes and pigments where the aldehyde group facilitates further condensation reactions.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for constructing complex biaryl structures in fine chemical synthesis.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating custom chemical libraries.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethoxy)Benzaldehyde
CAS No.	468075-02-7
Molecular Formula	C8H4ClF3O2
Molecular Weight	224.56 g/mol
Synonyms	2-Chloro-α,α,α-trifluoro-p-anisaldehyde; 5-(Trifluoromethoxy)-2-chlorobenzaldehyde; Benzaldehyde, 2-chloro-5-(trifluoromethoxy)-; 2-Chloro-5-trifluoromethoxybenzaldehyde; α,α,α-Triflu-2-chloro-5-methoxybenzaldehyde (obsolete); 2-Chloro-5-(trifluoromethoxy)benzene-1-carbaldehyde (IUPAC); 2-Chloro-5-(trifluoromethoxy)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-5-(Trifluoromethoxy)Benzaldehyde adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.