Description

4-Bromo-2-Chlorobenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its trifluoromethyl and halogen substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity.
• Material Science Precursor: Serves as a monomer or building block for specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions to create complex biaryl structures.
• Functional Dye Manufacturing: Employed in the synthesis of advanced dyes and pigments with specific light-absorption properties.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D labs for methodology development and library synthesis.

Basic Information

Product Name	4-Bromo-2-Chlorobenzotrifluoride
CAS No.	467435-07-0
Molecular Formula	C7H3BrClF3
Molecular Weight	259.45 g/mol
Synonyms	2-Chloro-4-bromobenzotrifluoride; 1-Bromo-3-chloro-4-(trifluoromethyl)benzene; 4-Bromo-2-chloro-α,α,α-trifluorotoluene; 2-Chloro-α,α,α-trifluoro-4-bromotoluene; Benzene, 1-bromo-3-chloro-4-(trifluoromethyl)-; 3-Chloro-4-bromobenzotrifluoride; BCFBT
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chlorobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended long-term storage temperature is between 2°C and 8°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.