Description

5-Amino-3-Fluoropyridine is a high-value fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a fluorine substituent on the pyridine ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as in material science for the development of specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent tags and molecular probes for diagnostic and research applications.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific fluorinated heterocycles.

Basic Information

Product Name	5-Amino-3-Fluoropyridine
CAS No.	462652-33-1
Molecular Formula	C5H5FN2
Molecular Weight	112.11 g/mol
Synonyms	3-Fluoro-5-aminopyridine; 3-Fluoropyridin-5-amine; 5-Amino-3-fluoropyridine; 5-Pyridinamine, 3-fluoro-; 3-Fluoro-5-pyridinamine
EINECS	Contact for details

Quality Control

Our 5-Amino-3-Fluoropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.