Description

2,3,4-Trifluoro-1,5-Diiodobenzene is a highly functionalized aromatic building block characterized by its unique combination of halogen substituents. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, particularly in cross-coupling reactions. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides where the fluorine and iodine atoms contribute to biological activity and environmental persistence profiles.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atoms are excellent substrates for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings, enabling precise carbon-carbon bond formation.
• Fluorine Chemistry Studies: An important reagent for investigating structure-activity relationships (SAR) and the effects of specific fluorine substitution patterns.
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for method development and quality control in related chemical processes.

Basic Information

Product Name	2,3,4-Trifluoro-1,5-Diiodobenzene
CAS No.	459425-36-6
Molecular Formula	C6HF3I2
Molecular Weight	399.87 g/mol
Synonyms	1,5-Diiodo-2,3,4-trifluorobenzene; 2,3,4-Trifluorobenzene-1,5-diyl diiodide; Benzene, 1,5-diiodo-2,3,4-trifluoro-; 2,3,4-Trifluoro-1,5-diiodo-benzene
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluoro-1,5-Diiodobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.