Description

1Alpha, 24, 25-Trihydroxy Vd2 is a high-purity, synthetic vitamin D analog with the CAS registry number 457048-34-9. This compound is critical for advanced research and development in endocrinology and metabolic pathways. It is primarily sought by pharmaceutical R&D teams, academic research institutions, and manufacturers of high-value nutraceutical intermediates for its specific biological activity.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) intermediate in the study of calcium homeostasis and bone metabolism.
• Biochemical Assays: Used as a precise ligand in receptor-binding studies and cell-based assays to investigate vitamin D receptor (VDR) activity.
• Nutraceutical Synthesis: Serves as a crucial precursor in the synthesis of specialized, high-potency vitamin D analogs for dietary supplements.
• Academic & Clinical Studies: Employed in universities and hospitals for fundamental research into diseases related to vitamin D deficiency and resistance.
• Metabolite Standard: Acts as an analytical standard in LC-MS and HPLC methods for the quantification of vitamin D metabolites in biological samples.

Basic Information

Product Name	1Alpha, 24, 25-Trihydroxy Vd2
CAS No.	457048-34-9
Molecular Formula	C27H44O4
Molecular Weight	432.64 g/mol
Synonyms	1α,24,25-Trihydroxyvitamin D2; 1α,24,25-Trihydroxyergocalciferol; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol; 1α,24R,25-Trihydroxyvitamin D2; Vitamin D2 metabolite
EINECS	Contact for details

Quality Control

Our 1Alpha, 24, 25-Trihydroxy Vd2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.