Description

3-Pyridinecarboxaldehyde, 2-Fluoro-4-Methoxy- (9Ci) is a high-purity, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and methoxy substituents, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of functionalized organic materials, including liquid crystals and electronic chemicals.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological systems and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific fluorinated heterocyclic architectures.

Basic Information

Product Name	3-Pyridinecarboxaldehyde, 2-Fluoro-4-Methoxy- (9Ci)
CAS No.	451459-05-5
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	2-Fluoro-4-methoxypyridine-3-carboxaldehyde; 2-Fluoro-4-methoxy-3-pyridinecarboxaldehyde; 3-Formyl-2-fluoro-4-methoxypyridine; 2-Fluoro-4-methoxy-3-formylpyridine; 2-Fluoro-4-methoxynicotinaldehyde; 2-Fluoro-4-methoxypyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarboxaldehyde, 2-Fluoro-4-Methoxy- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is supplied with each shipment to guarantee traceability and consistency for your critical synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.