Description

2-Fluoro-5-(4-Methoxyphenyl)Pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a fluorine atom with a methoxyphenyl substituent, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs.
• Chemical Biology Probes: Utilized to develop fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-5-(4-Methoxyphenyl)Pyridine
CAS No.	444120-93-8
Molecular Formula	C₁₂H₁₀FNO
Molecular Weight	203.21 g/mol
Synonyms	5-(4-Methoxyphenyl)-2-fluoropyridine; 2-Fluoro-5-(4'-methoxyphenyl)pyridine; 2-Fluoro-5-(p-methoxyphenyl)pyridine; 444120-93-8; Pyridine, 2-fluoro-5-(4-methoxyphenyl)-; 2-Fluoro-5-(4-methoxy-phenyl)-pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(4-Methoxyphenyl)Pyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed impurity profiling available. Certificates of Analysis (COA) are provided with each shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.