Description

3-Oxo-3,4-Dihydro-2H-Benzo[1,4]Thiazine-6-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile handle for introducing the benzo[1,4]thiazine pharmacophore into target molecules, enabling the development of novel compounds with specific biological activities. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways where the benzo[1,4]thiazine core is pharmacologically relevant.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides, leveraging its reactive sulfonyl chloride group for structural diversification.
• Material Science Research: Employed as a monomer or functionalization agent in the development of advanced polymers or organic electronic materials with specific optoelectronic properties.
• Chemical Biology Probes: Acts as a versatile linker for creating activity-based probes or affinity tags to study enzyme function and protein interactions in biological systems.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals for clients.

Basic Information

Product Name	3-Oxo-3,4-Dihydro-2H-Benzo[1,4]Thiazine-6-Sulfonyl Chloride
CAS No.	443955-56-4
Molecular Formula	C8H6ClNO3S2
Molecular Weight	263.72 g/mol
Synonyms	2H-1,4-Benzothiazine-6-sulfonyl chloride, 3,4-dihydro-3-oxo-; 3-Oxo-3,4-dihydro-2H-1,4-benzothiazine-6-sulfonyl chloride; 6-(Chlorosulfonyl)-3,4-dihydro-2H-1,4-benzothiazin-3-one; Benzo[1,4]thiazine-6-sulfonyl chloride, 3,4-dihydro-3-oxo-; 443955-56-4; CAS 443955-56-4
EINECS	Contact for details

Quality Control

Our 3-Oxo-3,4-Dihydro-2H-Benzo[1,4]Thiazine-6-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.