Description

Cdk1/2Inhibitoriii CAS NO 443798-55-8 is a potent and selective small-molecule inhibitor targeting cyclin-dependent kinases 1 and 2 (CDK1/2), key regulators of the cell cycle. This compound is a critical research tool for investigating cell cycle progression, proliferation mechanisms, and the development of targeted cancer therapies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in oncology, molecular biology, and drug discovery programs.

Application

• Biochemical Research: Used as a selective inhibitor to study the specific roles and signaling pathways of CDK1 and CDK2 in vitro.
• Cancer Research & Drug Discovery: Serves as a lead compound or reference standard in the development of novel anti-cancer therapeutics targeting cell cycle dysregulation.
• Cell Biology Studies: Applied to synchronize cells at specific cell cycle checkpoints (e.g., G1/S or G2/M phases) for mechanistic studies.
• Target Validation: Employed in functional assays to validate CDK1/2 as therapeutic targets in various disease models.
• High-Throughput Screening (HTS): Used as a control or reference compound in screening campaigns to identify new CDK inhibitors.
• Apoptosis Research: Investigated for its role in inducing cell cycle arrest and apoptosis in tumor cell lines.

Basic Information

Product Name	Cdk1/2Inhibitoriii
CAS No.	443798-55-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CDK1/2 Inhibitor III; 3-((6,7-Dimethoxy-9-oxo-9H-xanthen-4-yl)oxy)-N,N-dimethylpropan-1-amine; Xanthen-9-one derivative; CDK Inhibitor; Seliciclib analog (research compound); Roscovitine-related inhibitor; Cyclin-dependent kinase inhibitor
EINECS	Contact for details

Quality Control

Our Cdk1/2Inhibitoriii is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.