Description

Rac n-Desisopropyl-n-Ethyl Acebutolol CAS NO 441019-91-6 is a key chemical intermediate and reference standard primarily used in pharmaceutical research and development. This compound is critical for analytical studies, method validation, and the synthesis of related active pharmaceutical ingredients (APIs). It is essential for pharmaceutical manufacturers, analytical laboratories, and R&D facilities focused on cardiovascular drug development and quality control processes.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments and the validation of testing methods (HPLC, GC-MS) in quality control laboratories.
• Chemical Intermediate: Serves as a crucial building block in the research-scale synthesis of β-blocker pharmaceuticals and their derivatives.
• Metabolite Studies: Employed in pharmacokinetic and drug metabolism research to understand the breakdown pathways of related pharmaceutical compounds.
• Impurity Profiling: Acts as a known impurity standard to monitor and control the quality of Acebutolol and similar active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: Utilized in investigative studies for developing new therapeutic agents within the cardiovascular drug class.

Basic Information

Product Name	Rac n-Desisopropyl-n-Ethyl Acebutolol
CAS No.	441019-91-6
Molecular Formula	C16H26N2O4
Molecular Weight	310.39 g/mol
Synonyms	N-Desisopropyl-N-ethyl Acebutolol; Acebutolol N-Desisopropyl-N-ethyl Impurity; Acebutolol Related Compound; 1-(2-Acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)ethanone; rac-Desethyl Desisopropyl Acebutolol; Acebutolol Metabolite; DL-n-Desisopropyl-n-Ethyl Acebutolol
EINECS	Contact for details

Quality Control

Our Rac n-Desisopropyl-n-Ethyl Acebutolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity assay and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.